Why Iodomarin® to supplement iodine?

Therefore it is very important to take care of nutritional supply of iodine in order to avoid the risk of developing the symptoms of so called iodine deficiency disorders.1,2 Especially if you are living in an iodine deficient area or if you have an increased need for iodine as you are e. g. pregnant or breast-feeding you should take care for your daily intake of iodine. Also for children up to 24 months need a proper amount of iodine every day.

If you could not meet the recommended intake of iodine by food, you should consider a supplementation of iodine for example with Iodomarin® to prevent iodine deficiency.

Why iodine is important: First of all iodine is necessary for normal production of thyroid hormones and consequent thyroid gland functions and is very important for proper growth and physical and mental development in the fetus during pregnancy, in new-born children and during early childhood. If an iodine deficiency occurs the symptoms can affect the school life and daily activities of school children and teenagers. But also in adults iodine is essential for a normal cognitive and neurological function as well as normal energy-metabolism.

A good choice to prevent an iodine deficiency with the possible results of the iodine deficiency disorders like a goitre and to improve reasoning abilities and cognitive functions is an oral supplementation with Iodomarin®.

Iodomarin® is a medicinal product and contains the active substance potassium iodide. It has two distinct therapeutic indications:

  • Prophylaxis of iodine deficiency (e. g. prophylaxis of goitre in iodine deficiency areas and after removal of iodine deficiency goitre)
  • Treatment of goitre in new-borns, children, adolescents and young adults

Goitre is mainly caused by iodine deficiency, but there can be other physiological causes of goitre as well. Iodomarin® is indicated in benign goitre in patients with normal thyroid gland function.

You can get Iodomarin® in two different dosages: Iodomarin® 100 with 131 μg potassium iodide (equivalent to 100 μg iodide) and Iodomarin® 200 with 262 μg potassium iodide (equivalent to 200 μg iodide). The two dosages of Iodomarin® offers you the right amount of iodine for your needs and helps to restore the appropriate iodine level in your body. Thus Iodomarin® can prevent iodine deficiency and its consequences. In addition the application as an oral supplementation with tablets is one of the easiest ways to ensure getting the adequate quantity of iodine every day.

- Iodomarin® is a medication which is trusted by patients as well as by doctors. For many years it is accepted and appreciated as an expert for iodine deficiency prevention and treatment. 12,13

Iodomarin® in a nutshell

  • Contains a specific dose of iodine in each tablet
  • Requires only singe dosing per day
  • Helps to replenish iodine deficiency in the body and prevent iodine deficiency
  • Helps to prevent goitre
  • Long-term usage possible

1. Iodomarin® 100

Each tablet of Iodomarin® 100 contains 131 μg potassium iodide which is equivalent to 100 μg iodide. For a dosage of 50 μg you can divide the tablet into two equal halves.

Dosage of Iodomarin® 100

The recommended dosage of Iodomarin® 100 depends on the indication and on your age.  

Indication

Age group

Daily dose of

Iodide (µg)

Iodomarin® 100

Goitre prophylaxis in iodine deficiency

Infants and children

50 – 100

½ -1 tablet

Adolescents and adults

100 – 200

1-2 tablets

Pregnant and breast-feeding women

200

2 tablets

Prophylaxis of new goitre growth after surgery or a treatment of iodine deficiency goitre with medicines

 

Not specified

100 - 200

1-2 tablets

Treatment of iodine deficiency goitre

New-borns, children, and adolescents

100 - 200

 

1-2 tablets

Young adults

300 - 500

3-5 tablets

Use of Iodomarin® 100

You should take the Iodomarin® 100 tablets after a meal with sufficient liquid, e. g. a glass of water. Generally Iodomarin® 100 must be administered for prophylaxis over a period of years, and, not uncommonly, for life. For treating goitre in new-borns the length of use is usually 2 – 4 weeks and 6 – 12 months or more in children, adolescents and adults.  

In some cases it is recommended to talk your doctor or pharmacist before taking Iodomarin® 100. Tell them if you are taking, have recently taken or might take any other medicines, especially if you are taking a therapy of an overactive thyroid with medicines or if you are pregnant or breast-feeding or if you think you might be pregnant or are planning to have a baby.

You will find more information about Iodomarin® 100 in the package leaflet.

2. Iodomarin® 200

Each tablet of Iodomarin® 200 contains 262 μg potassium iodide which is equivalent to 200 μg iodide. For a dosage of 100 μg you can divide the tablet into two equal halves.

Dosage of Iodomarin® 200

The recommended dosage of Iodomarin® 200 depends on the indication and on your age.

Indication

Age group

Daily dose of

Iodide (µg)

Iodomarin® 200

Goitre prophylaxis in iodine deficiency

Infants and children

Up to 100

½ tablet

Adolescents and adults

100 – 200

½ -1 tablet

Pregnant and breast-feeding women

200

1 tablet

Prophylaxis of new goitre growth after surgery or a treatment of iodine deficiency goitre with medicines

 

Not specified

100 - 200

½ -1 tablet

Treatment of iodine deficiency goitre

New-borns, children, and adolescents

100 - 200

½ -1 tablet

Young adults

300 - 500

1 ½ -2 ½ tablets

Use of Iodomarin® 200

You should take the Iodomarin® 200 tablets after a meal with sufficient liquid, e. g. a glass of water. Generally Iodomarin® 200 must be administered for prophylaxis over a period of years, and not uncommonly for life. For treating a goitre in new-borns the length of use is usually 2 – 4 weeks and 6 – 12 months or more in children, adolescents and adults.

Before you take Iodomarin® 200 is it important that you talk to your doctor or your pharmacist. Tell them if you are taking, have recently taken or might take any other medicines, especially if you are taking a therapy of an overactive thyroid with medicines or if you are pregnant or breast-feeding or if you think you might be pregnant or are planning to have a baby.

You will find more information about Iodomarin® 200 in the package leaflet.

3. Prophylaxis of goitre

Iodomarin® is an oral iodine supplementation and can be used for prophylaxis of iodine deficiency. It is approved for two medical indications to provide your health:

  • Prophylaxis of goitre in iodine deficiency areas
  • Prophylaxis of a recurrence of goitre after removal of iodine deficiency goitre

The recommended dosage for the prophylaxis of goitre depends on your age:

Age group

Daily dose of

Iodide (µg)

Iodomarin® 100

Iodomarin® 200

Infants and children

50 - 100

½ -1 tablet

½ tablet

Adolescents and adults

100 – 200

1-2 tablets

½ -1 tablet

Pregnant and breast-feeding women

200

2 tablets

1 tablet

For recurrence prophylaxis after removal of iodine deficiency goitre you should take 100 – 200 μg, which is equivalent to 1 – 2 tablets of Iodomarin® 100 and ½ - 1 tablet of Iodomarin® 200, respectively – depending on your age group.

In general you have to take Iodomarin® as an additional supplementation for prophylaxis of goitre over a period of years, not uncommonly for life, unless a drastic dietary or geographic change in your location occurs. This means that you, for example, move to an iodine rich environment such as near coastal regions and eat more fish.

4. Iodine deficiency disease: goitre

Goitre is an enlargement of the thyroid gland beyond normal and healthy sizes. This enlargement may be diffuse, this means without nodules, or have a uni-nodular or multinodular pattern.

 

Normally sized thyroid
Enlarged thyroid


In most cases a goitre doesn’t lead to any symptoms, but if the enlargement of the thyroid gland causes a mechanical compression of other neighbouring structures, it can lead to symptoms like difficulties in breathing (dyspnoea) or swallowing (dysphagia).

Causes for a goitre

It can be caused by numerous reasons, but one of the major causes of goitre is iodine deficiency, which leads to a so-called iodine-deficiency goitre. Other conditions or disorders that can lead to a goitre are for example:

  • Autoimmune thyroiditis
  • De Quervain’s thyroiditis
  • Riedel’s thyroiditis
  • Thyroid cyst
  • Impaired L-T4 biosynthesis
  • L-T4 resistance
  • Acromegaly

In addition, some drugs such as lithium may also induce goitre. Furthermore certain foodstuffs also called natural goitrogens such as cassava and soy may increase the size of the thyroid.

Goitre incidence varies greatly throughout the world. In Germany, for example, a cohort study showed that around 35% of inhabitants had an incidence of goitre. In areas with severe iodine deficiency, the prevalence of goitres can be as high as 80%. 

Treatment of a goitre

The treatment of goitre depends on its cause. In most cases treatment with iodide or levothyroxine is sufficient. If the goitre causes symptoms like breathing or swallowing problems, radioiodine therapy which decreases the size of the thyroid or surgery might be necessary.

The recommended dosage for the treatment of goitre with Iodomarin® depends on your age:

 

Age group

Daily dose of

Iodide (µg)

Iodomarin® 100

Iodomarin® 200

New-born, children and adolescents

100 – 200

1 - 2 tablets

½ - 1 tablet

Young adults

300 – 500

3 - 5 tablets

 1 ½ -2 ½ tablets

In general you have to take Iodomarin® as an additional supplementation for the treatment of goitre over a period of years, not uncommonly for life, unless a drastic dietary or geographic change in your location occurs. This means that you, for example, move to an iodine rich environment such as near coastal regions and eat more fish rich in iodine.

5. When is Iodomarin® contraindicated?

There are some conditions where you should not take Iodomarin® 100/200:

  • If you are allergic to potassium iodide or any of the other ingredients
  • In a manifestly overactive thyroid (with complaints)
  • In a latently overactive thyroid (without complaints) in a dosage of over 150 μg iodine per day
  • In benign, hormone-forming growth or uncontrolled hormone-forming areas of the thyroid in a dosage of 300 – 1,000 μg iodine per day (except in treatment before surgery)

Please note that the Iodomarin® 100/200 tablets contain lactose.

Possible side effects

Like all medicines, Iodomarin® 100/200 can cause side effects, although not everybody will get them. When iodide is used for prophylaxis in every age range, undesirable effects are not expected. However, in the presence of large uncontrolled hormone-forming areas in the thyroid and daily iodine administration of more than 150 μg, an overactive thyroid becoming manifest cannot be ruled out completely.

In very rare cases, which means in less than 1 in 10,000 people taking Iodomarin® 100/200 the following side effects could occur:

  • Iodine-induced rhinitis
  • Skin reactions
  • Swelling of the skin or mucous membranes
  • Fever
  • Acne
  • Salivary gland swelling
  • Iodine-induced overactive thyroid (when used for the therapy of goitre in adults)

If you are taking Iodomarin® 100/200 and get any side effects, talk to your doctor or pharmacist. This included any side effects not listed here.

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